NUMB antibody (AA 1-30)

Catalog No. ABIN3032082

This anti-NUMB antibody is a Rabbit Polyclonal antibody detecting NUMB in WB, IHC and ELISA. Suitable for Human.

Quick Overview for NUMB antibody (AA 1-30) (ABIN3032082)

Target: NUMB (Numb Homolog (NUMB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUMB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-NUMB Antibody

Binding Specificity: AA 1-30

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat

Purification: Purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this NUMB antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the NUMB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NUMB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for NUMB

Target: NUMB (Numb Homolog (NUMB))

Alternative Name: NUMB

Background: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.

UniProt: P49757

Pathways: Cell-Cell Junction Organization