PAK2 antibody (AA 192-222)

Catalog No. ABIN3032117

The Rabbit Polyclonal anti-PAK2 antibody has been validated for WB, ELISA and IHC. It is suitable to detect PAK2 in samples from Human.

Quick Overview for PAK2 antibody (AA 192-222) (ABIN3032117)

Target: PAK2 (P21-Activated Kinase 2 (PAK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PAK2 Antibody

Binding Specificity: AA 192-222

Purification: Purified

Immunogen: A portion of amino acids 192-222 from the human protein was used as the immunogen for this PAK2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PAK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PAK2

Target: PAK2 (P21-Activated Kinase 2 (PAK2))

Alternative Name: PAK2

Background: PAK2, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. PAK2 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Expression is ubiquitous, with higher levels seen in skeletal muscle, ovary, thymus and spleen. PAK2 is autophosphorylated when activated by CDC42/p21. The protein structure contains 1 CRIB domain.

UniProt: Q13177

Pathways: MAPK Signaling, RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha