PAK4 antibody (AA 187-216)

Catalog No. ABIN3032118

This anti-PAK4 antibody is a Rabbit Polyclonal antibody detecting PAK4 in WB, ELISA and FACS. Suitable for Human and Mouse.

Quick Overview for PAK4 antibody (AA 187-216) (ABIN3032118)

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-PAK4 Antibody

Binding Specificity: AA 187-216

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 187-216 from the mouse protein was used as the immunogen for this Pak4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Pak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Pak4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PAK4

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Alternative Name: Pak4

Background: Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).

UniProt: Q8BTW9

Pathways: RTK Signaling