PAX6 antibody (C-Term)

Catalog No. ABIN3032131

This Rabbit Polyclonal antibody specifically detects PAX6 in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for PAX6 antibody (C-Term) (ABIN3032131)

Target: PAX6 (Paired Box 6 (PAX6))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PAX6 Antibody

Binding Specificity: AA 404-436, C-Term

Cross-Reactivity (Details): Expected species reactivity: Bovine, Chicken, Human, Rat, Xenopus, Zebrafish

Purification: Antigen affinity purified

Immunogen: This mouse Pax6 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 404-436 amino acids from the C-terminal region of mouse Pax6.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Pax6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Pax6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Alternative Name: Pax6

Background: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity).

UniProt: P63015

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis