ATF2 antibody (pSer322)

Catalog No. ABIN3029846

The Rabbit Polyclonal anti-ATF2 antibody has been validated for ELISA and DB. It is suitable to detect ATF2 in samples from Human.

Quick Overview for ATF2 antibody (pSer322) (ABIN3029846)

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF2 antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Product Details anti-ATF2 Antibody

Binding Specificity: pSer322

Purification: Antigen affinity purified

Immunogen: This phospho-ATF2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS322 of human ATF2.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-ATF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-ATF2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ATF2

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Alternative Name: ATF2

Background: ATF2 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.

UniProt: P15336

Pathways: MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades