WEE1 antibody (pSer123)

Catalog No. ABIN3029618

The Rabbit Polyclonal anti-WEE1 antibody is suitable to detect WEE1 in samples from Human. It has been validated for ELISA, IHC and DB.

Quick Overview for WEE1 antibody (pSer123) (ABIN3029618)

Target: WEE1 (WEE1 Homolog (S. Pombe) (WEE1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WEE1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Dot Blot (DB)

Product Details anti-WEE1 Antibody

Binding Specificity: pSer123

Purpose: Phospho-Wee1 Antibody (pS123)

Purification: Antigen affinity

Immunogen: This phospho-Wee1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS123 of human Wee1.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-Wee1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-Wee1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for WEE1

Target: WEE1 (WEE1 Homolog (S. Pombe) (WEE1))

Alternative Name: Wee1

Background: This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

UniProt: P30291

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase