PINK1
Reactivity: Human
WB, IHC, ICC, IF
Host: Mouse
Monoclonal
S4-15
PE
Application Notes
Titration of the PINK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the PINK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
PINK1
(PTEN Induced Putative Kinase 1 (PINK1))
Alternative Name
PINK
Background
Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.