PINK1 antibody (AA 493-526)

Catalog No. ABIN3032403

This anti-PINK1 antibody is a Rabbit Polyclonal antibody detecting PINK1 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for PINK1 antibody (AA 493-526) (ABIN3032403)

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PINK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PINK1 Antibody

Binding Specificity: AA 493-526

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 493-526 from the human protein was used as the immunogen for this PINK1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PINK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PINK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PINK1

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Alternative Name: PINK1

Background: Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.

UniProt: Q9BXM7

Pathways: Autophagy