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PKM2 antibody (AA 460-489)

Name: PKM2 antibody (AA 460-489)
SKU: ABIN3032238
Price: 649.42 USD
Availability: InStock

PKM2 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

Western blot analysis of PKM2 antibody and CEM lysate. (PKM2 antibody (AA 460-489))

IHC analysis of FFPE human breast carcinoma tissue stained with PKM2 antibody (PKM2 antibody (AA 460-489))

IHC

3 images

Catalog No. ABIN3032238

Datasheet as PDF

Target See all PKM2 Antibodies

PKM2 (Pyruvate Kinase M2 (PKM2))
Binding Specificity
21

16

9

8

6

6

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 460-489
Reactivity
102

63

51

4

4

2

2

2

2

2

1

1

1
Human
Host
80

22

5
Rabbit
Compatible Secondaries
Clonality
86

21
Polyclonal
Conjugate
56

5

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1
This PKM2 antibody is un-conjugated
Application
80

29

27

27

24

15

15

13

9

8

7

5

2

2

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity (Details)

Expected species reactivity: Rabbit

Purification

Purified

Immunogen

A portion of amino acids 460-489 from the human protein was used as the immunogen for this PKM2 antibody.

Isotype

Ig Fraction

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anti-Pyruvate Kinase M2 (PKM2) (AA 294-470) antibody
PKM2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 141-248) antibody
PKM2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 476-505), (C-Term) antibody
PKM2 Reactivity: Human, Mouse, Rat, Monkey WB, IHC (p), IF Host: Rabbit Polyclonal RB3697 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibody
PKM2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibody
PKM2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB18405 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibody
PKM2 Reactivity: Human WB, IHC, ELISA, FACS Host: Rabbit Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibody
PKM2 Reactivity: Human, Mouse, Rat, Primate WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibody
PKM2 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IHC (p), IF (p), IF (cc), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 116-145), (N-Term) antibody
PKM2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB15338 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 121-151), (N-Term) antibody
PKM2 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB5870 unconjugated

Application Notes

Titration of the PKM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions

For Research Use only
Format

Liquid

Buffer

In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Aliquot the PKM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target

PKM2 (Pyruvate Kinase M2 (PKM2))

Alternative Name

PKM2 (PKM2 Products)

Background

PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

UniProt

P14618

Pathways

Warburg Effect