Progesterone Receptor antibody (AA 816-843)

Catalog No. ABIN3029751

This anti-Progesterone Receptor antibody is a Rabbit Polyclonal antibody detecting Progesterone Receptor in WB, ELISA and IF. Suitable for Human.

Quick Overview for Progesterone Receptor antibody (AA 816-843) (ABIN3029751)

Target: Progesterone Receptor (PGR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-Progesterone Receptor Antibody

Binding Specificity: AA 816-843

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 816-843 from the human protein was used as the immunogen for this PR antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: Progesterone Receptor

Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration