PRMT1 antibody (AA 316-347)

Catalog No. ABIN3032354

The Rabbit Polyclonal anti-PRMT1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect PRMT1 in samples from Human.

Quick Overview for PRMT1 antibody (AA 316-347) (ABIN3032354)

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PRMT1 Antibody

Binding Specificity: AA 316-347

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat

Purification: Purified

Immunogen: A portion of amino acids 316-347 from the human protein was used as the immunogen for this PRMT1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PRMT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PRMT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PRMT1

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Alternative Name: PRMT1

Background: Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

UniProt: Q99873