RBPMS antibody (AA 166-193)

Catalog No. ABIN3032494

This Rabbit Polyclonal antibody specifically detects RBPMS in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for RBPMS antibody (AA 166-193) (ABIN3032494)

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBPMS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RBPMS Antibody

Binding Specificity: AA 166-193

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 166-193 from the human protein was used as the immunogen for this RBPMS antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the RBPMS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the RBPMS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for RBPMS

Target: RBPMS (RNA Binding Protein with Multiple Splicing (RBPMS))

Alternative Name: RBPMS

Background: Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.

UniProt: Q93062