Ret Proto-Oncogene antibody (AA 1012-1042)

Catalog No. ABIN3032460

The Rabbit Polyclonal anti-Ret Proto-Oncogene antibody (ABIN3032460) specifically detects Ret Proto-Oncogene in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for Ret Proto-Oncogene antibody (AA 1012-1042) (ABIN3032460)

Target: Ret Proto-Oncogene (RET)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ret Proto-Oncogene antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Ret Proto-Oncogene Antibody

Binding Specificity: AA 1012-1042

Purpose: RET Antibody

Purification: Purified

Immunogen: A portion of amino acids 1012-1042 from the human protein was used as the immunogen for this RET antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the RET antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the RET antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Ret Proto-Oncogene

Target: Ret Proto-Oncogene (RET)

Alternative Name: RET

Background: RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.

UniProt: P07949

Pathways: RTK Signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation