Retinoblastoma Protein (Rb) antibody (AA 858-886)
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- Target See all Retinoblastoma Protein (Rb) (Rb Protein) Antibodies
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
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Binding Specificity
- AA 858-886
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Retinoblastoma Protein (Rb) antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Cross-Reactivity (Details)
- Expected species reactivity: Rat
- Purification
- Purified
- Immunogen
- A portion of amino acids 858-886 from the human protein was used as the immunogen for this Retinoblastoma antibody.
- Isotype
- Ig Fraction
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anti-Retinoblastoma Protein (Rb Protein) (pSer811) antibody
Rb Protein Reactivity: Human ELISA, IHC, IF, DB Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 586-615) antibodyRb Protein Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (Cleavage Site) antibodyRb Protein Reactivity: Human, Mouse WB, IHC Host: Mouse Monoclonal 172C1094 unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer608) antibodyRb Protein Reactivity: Human ELISA, IHC, DB Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer780) antibodyRb Protein Reactivity: Human ELISA, IHC, DB Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer788) antibodyRb Protein Reactivity: Human ELISA, IHC, DB Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) antibodyRb Protein Reactivity: Human ELISA, IHC Host: Mouse Monoclonal 7E4B8 unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 251-268) antibodyRb Protein Reactivity: Human, Mouse, Rat, Cow, Dog, Monkey, Pig, Bat, Horse WB Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (N-Term) antibodyRb Protein Reactivity: Human, Mouse, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (C-Term) antibodyRb Protein Reactivity: Human, Cow, Dog, Pig, Bat, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Titration of the Retinoblastoma antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the Retinoblastoma antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
- Alternative Name
- Retinoblastoma (Rb Protein Products)
- Background
- RB1/Retinoblastoma is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.
- UniProt
- P06400
- Pathways
- Mitotic G1-G1/S Phases
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