SGK1 antibody (AA 323-352)

Catalog No. ABIN3032549

The Rabbit Polyclonal anti-SGK1 antibody has been validated for WB and ELISA. It is suitable to detect SGK1 in samples from Human.

Quick Overview for SGK1 antibody (AA 323-352) (ABIN3032549)

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SGK1 Antibody

Binding Specificity: AA 323-352

Cross-Reactivity (Details): Expected species reactivity: Rat, Primate

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 323-352 from the mouse protein was used as the immunogen for this Sgk1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Sgk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Sgk1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SGK1

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Alternative Name: Sgk1

Background: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. This enzyme is activated by protein phosphorylation and degraded via the ubiquitination and proteasome pathway. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene was identified on chromosome 12.

UniProt: Q9WVC6

Pathways: MAPK Signaling, Notch Signaling, Steroid Hormone Mediated Signaling Pathway