SIRT3 antibody (AA 56-84)

Catalog No. ABIN3032589

The Rabbit Polyclonal anti-SIRT3 antibody (ABIN3032589) specifically detects SIRT3 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for SIRT3 antibody (AA 56-84) (ABIN3032589)

Target: SIRT3 (Sirtuin 3 (SIRT3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIRT3 Antibody

Binding Specificity: AA 56-84

Purpose: SIRT3 Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 56-84 from the human protein was used as the immunogen for this SIRT3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SIRT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SIRT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Alternative Name: SIRT3

Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

UniProt: Q9NTG7