SLUG antibody (AA 98-129)
Quick Overview for SLUG antibody (AA 98-129) (ABIN3032658)
Target
See all SLUG (SNAI2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 98-129
-
Cross-Reactivity (Details)
- Expected species reactivity: Bovine
-
Purification
- Purified
-
Immunogen
- A portion of amino acids 98-129 from human SNAI2 was used as the immunogen for this SLUG antibody.
-
Isotype
- Ig Fraction
-
-
-
-
Application Notes
- Titration of the SLUG antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Aliquot the SLUG antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
-
Alternative Name
- SLUG (SNAI2)
-
Background
- SLUG/SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress < a href=../search_result.php?search_txt=e cadherin>E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects. [Wiki]
-
UniProt
- O43623
Target
-