SMAD1 antibody (AA 154-187)
Quick Overview for SMAD1 antibody (AA 154-187) (ABIN3032611)
Target
See all SMAD1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 154-187
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Purpose
- Smad1 Antibody
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Purification
- Antigen affinity
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Immunogen
- This Smad1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 154-187 amino acids from the central region of mouse Smad1.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the Smad1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Smad1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
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Alternative Name
- Smad1
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Background
- Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity). May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (By similarity). May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. [UniProt]
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UniProt
- P70340
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Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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