SOX4 antibody (AA 269-297)

Catalog No. ABIN3032700

Product Details anti-SOX4 Antibody

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Binding Specificity: AA 269-297

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified

Immunogen: A portion of amino acids 269-297 from the human protein was used as the immunogen for this SOX4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SOX4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SOX4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SOX4

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Alternative Name: SOX4 (SOX4 Products)

Synonyms: EVI16 antibody, AA682046 antibody, Sox-4 antibody, sox4 antibody, wu:fb82f08 antibody, wu:fq41g10 antibody, zgc:65850 antibody, zgc:77392 antibody, SRY-box 4 antibody, SRY box 4 antibody, SRY (sex determining region Y)-box 4 antibody, SRY (sex determining region Y)-box 4a antibody, SOX4 antibody, Sox4 antibody, sox4a antibody

Background: SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.

UniProt: Q06945