NCOA1 antibody (AA 594-625)

Catalog No. ABIN3032055

The Rabbit Polyclonal anti-NCOA1 antibody (ABIN3032055) specifically detects NCOA1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for NCOA1 antibody (AA 594-625) (ABIN3032055)

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NCOA1 Antibody

Binding Specificity: AA 594-625

Purpose: SRC-1 Antibody

Purification: Purified

Immunogen: A portion of amino acids 594-625 from the human protein was used as the immunogen for this SRC-1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SRC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SRC-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NCOA1

Target: NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

Alternative Name: SRC-1

Background: Nuclear receptor coactivator 1/SRC-1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.

UniProt: Q15788

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha