SUMO1 antibody (AA 1-30)

Catalog No. ABIN3032639

The Rabbit Polyclonal anti-SUMO1 antibody is suitable to detect SUMO1 in samples from Human. It has been validated for WB, IHC, IF and ELISA.

Quick Overview for SUMO1 antibody (AA 1-30) (ABIN3032639)

Target: SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-SUMO1 Antibody

Binding Specificity: AA 1-30

Purpose: SUMO-1 Antibody

Cross-Reactivity (Details): Expected species reactivity: Bovine, Mouse, Pig, Rat

Purification: Antigen affinity

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this SUMO-1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the SUMO-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the SUMO-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SUMO1

Target: SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

Alternative Name: SUMO-1

Background: This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.

UniProt: P63165

Pathways: M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway