SUMO3 antibody (AA 38-64)
Quick Overview for SUMO3 antibody (AA 38-64) (ABIN3032652)
Target
See all SUMO3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 38-64
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Purification
- Purified
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Immunogen
- A portion of amino acids 38-64 from the human protein was used as the immunogen for this SUMO-3 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the SUMO-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the SUMO-3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))
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Alternative Name
- SUMO-3
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Background
- SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
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UniProt
- P55854
Target
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