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SYK antibody (AA 195-223)

This Rabbit Polyclonal antibody specifically detects SYK in WB and ELISA. It exhibits reactivity toward Human and Mouse.

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Catalog No. ABIN3032716

$612.54

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Quick Overview for SYK antibody (AA 195-223) (ABIN3032716)

Target

See all SYK Antibodies

SYK (Spleen tyrosine Kinase (SYK))

Reactivity

Human, Mouse

Host

Rabbit

Clonality

Polyclonal

Conjugate

This SYK antibody is un-conjugated

Application

Western Blotting (WB), ELISA

Discover our top product SYK Primary Antibody

Binding Specificity
37

31

20

14

13

10

8

8

7

5

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 195-223

Purpose

Syk Antibody

Predicted Reactivity

Chicken,Rat

Purification

Antigen affinity

Immunogen

A portion of amino acids 195-223 from the mouse protein was used as the immunogen for this Syk antibody.

Isotype

Ig Fraction
anti-Spleen tyrosine Kinase (SYK) (AA 5-360) antibody
SYK Reactivity: Human, Mouse, Rat WB, IP, IHC (p), ICC Host: Mouse Monoclonal SYK-01 unconjugated

anti-Spleen tyrosine Kinase (SYK) (Internal Region) antibody
SYK Reactivity: Human, Mouse, Rat WB, IF, IP, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibody
SYK Reactivity: Human ELISA, ICC, FACS Host: Mouse Monoclonal 2G11E6 unconjugated

anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibody
SYK Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 3D1G10 unconjugated

anti-Spleen tyrosine Kinase (SYK) (AA 387-417), (C-Term) antibody
SYK Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB03097 unconjugated

anti-Spleen tyrosine Kinase (SYK) (AA 10-635) antibody
SYK Reactivity: Human, Mouse, Rat WB, IHC, ELISA, FACS Host: Rabbit Polyclonal unconjugated

anti-Spleen tyrosine Kinase (SYK) (AA 374-635) antibody
SYK Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Spleen tyrosine Kinase (SYK) (pTyr323) antibody
SYK Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Spleen tyrosine Kinase (SYK) (AA 1-635) antibody
SYK Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated

anti-Spleen tyrosine Kinase (SYK) (pTyr525), (pTyr526) antibody
SYK Reactivity: Human WB, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Application Notes

Titration of the Syk antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions

For Research Use only
Format

Liquid

Buffer

In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freeze-thaw cycles

Storage

-20 °C

Storage Comment

Aliquot the Syk antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target

SYK (Spleen tyrosine Kinase (SYK))

Alternative Name

Syk

Background

Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion. Phosphorylates USP25 and regulates its intracellular levels (By similarity).

UniProt

P48025

Pathways

Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling