SYK antibody (AA 268-305)
Quick Overview for SYK antibody (AA 268-305) (ABIN3032715)
Target
See all SYK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 268-305
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Purpose
- SYK Antibody
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Predicted Reactivity
- Pig
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 268-305 from the human protein was used as the immunogen for this SYK antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the SYK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles
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Storage
- -20 °C
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Storage Comment
- Aliquot the SYK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SYK (Spleen tyrosine Kinase (SYK))
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Alternative Name
- SYK
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Background
- This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
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UniProt
- P43405
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Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
Target
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