TCF4 antibody (AA 48-73)

Catalog No. ABIN3029194

Product Details anti-TCF4 Antibody

Target: TCF4 (Transcription Factor 4 (TCF4))

Binding Specificity: AA 48-73

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 48-73 from the human protein was used as the immunogen for this TCF4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the TCF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TCF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Alternative Name: TCF4 (TCF4 Products)

Synonyms: E2-2 antibody, ITF-2 antibody, ITF2 antibody, PTHS antibody, SEF-2 antibody, SEF2 antibody, SEF2-1 antibody, SEF2-1A antibody, SEF2-1B antibody, TCF-4 antibody, bHLHb19 antibody, 5730422P05Rik antibody, ASP-I2 antibody, E2.2 antibody, ITF-2b antibody, ME2 antibody, MITF-2A antibody, MITF-2B antibody, TFE antibody, Tcf-4 antibody, TCF7L2 antibody, XE2 antibody, Xtcf-4 antibody, Xtcf4 antibody, e2-A antibody, tcf-4 antibody, transcription factor 4 antibody, transcription factor 4 S homeolog antibody, TCF4 antibody, Tcf4 antibody, tcf4 antibody, tcf4.S antibody

Background: TCF4 is transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome.

UniProt: P15884

Pathways: WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus