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TEK antibody (AA 758-789)

This anti-TEK antibody is a Rabbit Polyclonal antibody detecting TEK in WB, ELISA and IHC. Suitable for Human.
Catalog No. ABIN3029103

Quick Overview for TEK antibody (AA 758-789) (ABIN3029103)

Target

See all TEK Antibodies
TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reactivity

  • 124
  • 61
  • 48
  • 22
  • 4
  • 3
Human

Host

  • 118
  • 21
  • 4
  • 3
  • 2
Rabbit

Clonality

  • 124
  • 24
Polyclonal

Conjugate

  • 77
  • 10
  • 8
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TEK antibody is un-conjugated

Application

  • 80
  • 56
  • 40
  • 40
  • 36
  • 32
  • 18
  • 13
  • 13
  • 12
  • 8
  • 7
  • 4
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Binding Specificity

    • 19
    • 19
    • 16
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 758-789

    Cross-Reactivity (Details)

    Expected species reactivity: Bovine

    Purification

    Purified

    Immunogen

    A portion of amino acids 758-789 from the human protein was used as the immunogen for this TIE2 antibody.

    Isotype

    Ig Fraction
  • Application Notes

    Titration of the TIE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Aliquot the TIE2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    TEK (TEK Tyrosine Kinase, Endothelial (TEK))

    Alternative Name

    TIE2

    Background

    The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

    UniProt

    Q02763

    Pathways

    RTK Signaling, Growth Factor Binding
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