TLR9 antibody (AA 842-870)

Catalog No. ABIN3029183

The Rabbit Polyclonal anti-TLR9 antibody is suitable to detect TLR9 in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for TLR9 antibody (AA 842-870) (ABIN3029183)

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-TLR9 Antibody

Binding Specificity: AA 842-870

Purpose: TLR9 Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 842-870 from the human protein was used as the immunogen for this TLR9 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the TLR9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TLR9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for TLR9

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Alternative Name: TLR9

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

UniProt: Q9NR96

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades