Thrombopoietin antibody (AA 243-273)
Quick Overview for Thrombopoietin antibody (AA 243-273) (ABIN3029127)
Target
See all Thrombopoietin (THPO) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 243-273
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Purpose
- Thrombopoietin Antibody / THPO
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Purification
- Purified
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Immunogen
- A portion of amino acids 243-273 from the human protein was used as the immunogen for this THPO antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the THPO antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles
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Storage
- -20 °C
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Storage Comment
- Aliquot the THPO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Thrombopoietin (THPO)
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Background
- Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO/Thrombopoietin is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. It is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.
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UniProt
- P40225
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Pathways
- JAK-STAT Signaling, Hormone Activity
Target
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