WEE1 antibody (AA 604-634)
Quick Overview for WEE1 antibody (AA 604-634) (ABIN3029620)
Target
See all WEE1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 604-634
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Purpose
- Wee1 Antibody
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse, Rat
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Purification
- Purified
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Immunogen
- A portion of amino acids 604-634 from the human protein was used as the immunogen for this Wee1 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the Wee1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Wee1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- WEE1 (WEE1 Homolog (S. Pombe) (WEE1))
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Alternative Name
- Wee1
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Background
- Wee1 is a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
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UniProt
- P30291
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Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
Target
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