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ADCY5 antibody

ADCY5 Reactivity: Human, Mouse, Rat WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN498295
  • Target See all ADCY5 Antibodies
    ADCY5 (Adenylate Cyclase 5 (ADCY5))
    Reactivity
    • 29
    • 29
    • 22
    • 5
    • 5
    Human, Mouse, Rat
    Host
    • 35
    • 4
    Rabbit
    Clonality
    • 36
    • 3
    Polyclonal
    Conjugate
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADCY5 antibody is un-conjugated
    Application
    • 28
    • 13
    • 13
    • 12
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of A Cyclase V/VI protein. (region surrounding Phe1052)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Also reacts to: ADCY6
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product ADCY5 Primary Antibody
  • Application Notes
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 -1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ADCY5 (Adenylate Cyclase 5 (ADCY5))
    Alternative Name
    Adenylate Cyclase Type 5 (ADCY5 Products)
    Synonyms
    AC5 antibody, ADCY5 antibody, si:dkeyp-60a7.2 antibody, FDFM antibody, AW121902 antibody, Ac5 antibody, RUT antibody, adenylate cyclase 5 antibody, ADCY5 antibody, adcy5 antibody, Adcy5 antibody
    Background
    A cyclase V, also known as ADCY5, is a 1,261 amino acid Adenylyl cyclase that localizes to cellular membranes and contains two guanylate cyclase domains. Similar to other A cyclase proteins, A cyclase V uses magnesium as a cofactor to catalyze the conversion of ATP to cAMP. A cyclase VI, also known as ADCY6 (adenylate cyclase type 6), is a 1,168 amino acid A cyclase that localizes to the membrane and contains two guanylate cyclase domains. Using magnesium as a cofactor, A cyclase VI functions as a calcium-inhibitable A cyclase that catalyzes the conversion of ATP to 3',5'-cyclic AMP and diphosphate and plays a role in a variety of events throughout the body. Multiple isoforms of A cyclase VI exist due to alternative splicing events.Synonyms: ADCY5, ATP pyrophosphate-lyase 5, Adenylate cyclase type V, Adenylyl cyclase 5
    Molecular Weight
    approx. 138 kDa
    Gene ID
    111
    NCBI Accession
    NP_899200
    UniProt
    O95622
    Pathways
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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