OXT antibody

Catalog No. ABIN498497

The Rabbit Polyclonal anti-OXT antibody is suitable to detect OXT in samples from Human and Rat. It has been validated for WB, IF and IHC (p).

Quick Overview for OXT antibody (ABIN498497)

Target: OXT (Oxytocin, Prepropeptide (OXT))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXT antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-OXT Antibody

Specificity: This antibody detects endogenous levels of Neurophysin I protein. (region surrounding Lys40)

Cross-Reactivity (Details): Species reactivity (tested):Human and Rat.

Purification: Affinity chromatography using epitope-specific immunogen.

Application Details

Application Notes: Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for OXT

Target: OXT (Oxytocin, Prepropeptide (OXT))

Alternative Name: Oxytocin-neurophysin 1

Background: The nonapeptide hormones Arginine Vasopressin (ARGVasopressin or AVP) and Oxytocin are synthesized in the supraoptic and paraventricular nuclei of the hypothalamus together with their respective Synonyms: Neurophysin 1, OT, OT-NPI, OXT, Oxytocin-neurophysin 1

Molecular Weight: approx. 20 kDa

Gene ID: 5020

NCBI Accession: NP_000906

UniProt: P01178

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour