IL13RA1
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
1F5
unconjugated
Application Notes
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.Synonyms: CT19, Cancer/testis antigen 19, IL-13R-alpha-1, IL-13RA-1, IL13 receptor alpha, IL13R, IL13RA, Interleukin-13 receptor alpha-1 chain