EPH Receptor B1 antibody

Catalog No. ABIN499010

The Rabbit Polyclonal anti-EPH Receptor B1 antibody is suitable to detect EPH Receptor B1 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for EPH Receptor B1 antibody (ABIN499010)

Target: EPH Receptor B1 (EPHB1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPH Receptor B1 Antibody

Specificity: This antibody detects endogenous levels of EphB1/2/3/4 protein. (region surrounding Tyr594)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.
Also reacts to: EphB2/3/4

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EPH Receptor B1

Target: EPH Receptor B1 (EPHB1)

Alternative Name: EPHB1

Background: Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.Synonyms: ELK, EPH2, EPHT2, Ephrin type-B receptor 1, HEK6, NET, Tyrosine-protein kinase receptor EPH-2

Molecular Weight: approx. 118 kDa

Gene ID: 2047

NCBI Accession: NP_004432

UniProt: P54762

Pathways: RTK Signaling