AGFG2 antibody

Catalog No. ABIN499086

Product Details anti-AGFG2 Antibody

Target: AGFG2 (ArfGAP with FG Repeats 2 (AGFG2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGFG2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects endogenous levels of Rabr protein. (region surrounding Val131)

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for AGFG2

Target: AGFG2 (ArfGAP with FG Repeats 2 (AGFG2))

Alternative Name: AGFG2 / HRBL (AGFG2 Products)

Synonyms: HRBL antibody, RABR antibody, A630095P14Rik antibody, Hrbl antibody, ArfGAP with FG repeats 2 antibody, AGFG2 antibody, Agfg2 antibody

Background: Rabr, also known as AGFG2 (Arf-GAP domain and FG repeats-containing protein 2), is a 481 amino acid member of the HIV-1 REV binding protein (HRB) family and has one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. Rabr shares 46 % identity with Rab. Both Rab and Rabr contain a zinc finger region near the N terminus, several phe-gly (FG) motifs, which is characteristic of nucleoporin-like proteins, and four NPF motifs located in the C-terminal region. Rabr interacts with Eps15 homology (EH) domains and plays a role in the REV export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs.Synonyms: Arf-GAP domain and FG repeats-containing protein 2, HIV-1 Rev-binding protein-like protein, RABR, Rev/Rex activation domain-binding protein related

Molecular Weight: approx. 49 kDa

Gene ID: 3268

NCBI Accession: NP_006067

UniProt: O95081