BCL2L10 antibody (N-Term)

Catalog No. ABIN499431

The Rabbit Polyclonal anti-BCL2L10 antibody (ABIN499431) specifically detects BCL2L10 in WB, IF and EIA. The antibody is reactive with Human samples.

Quick Overview for BCL2L10 antibody (N-Term) (ABIN499431)

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L10 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-BCL2L10 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to Bcl-B.

Purification: Affinity chromatography purified via peptide column

Immunogen: Bcl-B antibody was raised against a 16 amino acid peptide from near the amino terminus of human Bcl-B.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: Bcl-B antibody can be used for the detection of Bcl-B at 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for BCL2L10

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Alternative Name: Bcl-2-Like 10

Background: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1. Despite its predicted molecular weight, Bcl-B is often at higher molecular weights, presumably due to post-translational modifications.Synonyms: Anti-apoptotic protein NrH, Apoptosis regulator Bcl-B, BCL2L10, BCLB, Bcl-B, Bcl2-L-10, NrH

Gene ID: 10017

NCBI Accession: NP_065129

UniProt: Q9HD36

Pathways: Positive Regulation of Endopeptidase Activity