EPH Receptor A10 antibody (N-Term)

Catalog No. ABIN499800

Product Details anti-EPH Receptor A10 Antibody

Target: EPH Receptor A10 (EPHA10)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A10 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to EphA10.

Purification: Affinity chromatography purified via peptide column

Immunogen: EphA10 antibody was raised against a 14 amino acid peptide of near the amino terminus of human EphA10.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for EPH Receptor A10

Target: EPH Receptor A10 (EPHA10)

Alternative Name: EphA10 (EPHA10 Products)

Synonyms: A330090H18 antibody, RGD1562679 antibody, EPH receptor A10 antibody, Eph receptor A10 antibody, EPHA10 antibody, Epha10 antibody

Background: Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL.Synonyms: EPH receptor A10, Ephrin type-A receptor 10, FLJ16103

Gene ID: 284656

NCBI Accession: NP_001092909

UniProt: Q4G0R4

Pathways: RTK Signaling