CD80 antibody (AA 111-265) (AbBy Fluor® 750)

Catalog No. ABIN4999625

This anti-CD80 antibody is a Rabbit Polyclonal antibody detecting CD80 in FACS and WB. Suitable for Human, Mouse and Rat.

Quick Overview for CD80 antibody (AA 111-265) (AbBy Fluor® 750) (ABIN4999625)

Target: CD80

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD80 antibody is conjugated to AbBy Fluor® 750

Application: Flow Cytometry (FACS), Western Blotting (WB)

Product Details anti-CD80 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 111-265

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD80

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CD80

Target: CD80

Alternative Name: CD80

Background:

Synonyms: B7, BB1, B7-1, B7.1, LAB7, CD28LG, CD28LG1, T-lymphocyte activation antigen CD80, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1, CD80

Background: Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.

Gene ID: 941

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints