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Cullin 2 antibody (AA 365-745) (AbBy Fluor® 750)

This Rabbit Polyclonal antibody specifically detects Cullin 2 in IF (cc) and IF (p). It exhibits reactivity toward Human.
Catalog No. ABIN5000712

Quick Overview for Cullin 2 antibody (AA 365-745) (AbBy Fluor® 750) (ABIN5000712)

Target

See all Cullin 2 (CUL2) Antibodies
Cullin 2 (CUL2)

Reactivity

  • 73
  • 41
  • 26
  • 7
  • 7
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
Human

Host

  • 70
  • 2
  • 1
Rabbit

Clonality

  • 62
  • 11
Polyclonal

Conjugate

  • 37
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cullin 2 antibody is conjugated to AbBy Fluor® 750

Application

  • 38
  • 27
  • 15
  • 13
  • 13
  • 12
  • 7
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

    • 14
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 365-745

    Predicted Reactivity

    Human,Mouse,Rat,Dog,Cow,Horse

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Cullin 2

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    Cullin 2 (CUL2)

    Alternative Name

    Cullin 2

    Background

    Synonyms: Cullin2, Cullin-2, CUL 2, MGC131970, CUL2_HUMAN.

    Background: Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.

    Gene ID

    8453

    Pathways

    M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
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