MARCH5 antibody (AbBy Fluor® 680)

Catalog No. ABIN5006555

The AbBy Fluor® 680-conjugated Rabbit Polyclonal anti-MARCH5 antibody (ABIN5006555) specifically detects MARCH5 in WB, IF (cc) and IF (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MARCH5 antibody (AbBy Fluor® 680) (ABIN5006555)

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH5 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MARCH5 Antibody (AbBy Fluor® 680)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MARCH5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MARCH5

Target: MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))

Alternative Name: MARCH5

Background:

Synonyms: E3 ubiquitin-protein ligase MARCH5, MARCH-V, Membrane-associated RING finger protein 5, Membrane-associated RING-CH protein V, RING finger protein 153.

Background: MARCH5 is a member of the E3 ubiquitin-protein ligase family. This mitochonrial E3 ubiquitin-protein ligase plays an importnat role in controlling the morphology of the mitochondria. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. MARCH5 has been shown to interact with MTFN2 and ubiquitinated forms of DRP1.

Gene ID: 54708