SIPA1L2 antibody (N-Term)

Catalog No. ABIN500718

Product Details anti-SIPA1L2 Antibody

Target: SIPA1L2 (Signal-Induced Proliferation-Associated 1 Like 2 (SIPA1L2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIPA1L2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat

Purification: Peptide affinity chromatography

Immunogen: SIPA1L2 antibody was raised against a 19 amino acid peptide from near the amino terminus of human SIPA1L2.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for SIPA1L2

Target: SIPA1L2 (Signal-Induced Proliferation-Associated 1 Like 2 (SIPA1L2))

Alternative Name: SIPA1L2 (SIPA1L2 Products)

Synonyms: SPAL2 antibody, BC058408 antibody, mKIAA1389 antibody, Sersap2 antibody, Spar2 antibody, signal induced proliferation associated 1 like 2 antibody, signal-induced proliferation-associated 1 like 2 antibody, signal-induced proliferation-associated 1-like protein 2 antibody, SIPA1L2 antibody, LOC100331556 antibody, sipa1l2 antibody, Sipa1l2 antibody

Background: Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.Synonyms: KIAA1389, SIPA1-like protein 2, Signal-induced proliferation-associated 1-like protein 2

Gene ID: 57568

NCBI Accession: NP_065859

UniProt: Q9P2F8