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SPRED2 antibody (Center)
SPRED2
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SPRED2 Antibody
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Target
See all SPRED2 Antibodies
SPRED2
(Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))
Binding Specificity
All epitopes for SPRED2 antibodies
Center
Reactivity
All reactivities for SPRED2 antibodies
Human
Host
All hosts for SPRED2 antibodies
Rabbit
Clonality
All clonalities for SPRED2 antibodies
Polyclonal
Conjugate
All conjugates for SPRED2 antibodies
This SPRED2 antibody is un-conjugated
Application
All applications for SPRED2 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects SPRED2. It is predicted to have no cross-reactivity to Spred1 or Spred3.
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Peptide affinity chromatography
Immunogen
Spred2 antibody was raised against a 13 amino acid peptide near the center of the human Spred2.
Isotype
IgG
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Discover our top product SPRED2 Primary Antibody
Alternatives
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anti-Sprouty-Related, EVH1 Domain Containing 2 (SPRED2) (AA 317-366) antibody
SPRED2
Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Bat, Hamster, Monkey, Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
ELISA. Western blot: 1 - 2 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for SPRED2
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Target
SPRED2
(Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))
Alternative Name
SPRED2 (SPRED2 Products )
Synonyms
SPRED2 antibody, Xspred2 antibody, spred-2 antibody, Xtspred2 antibody, spred2 antibody, wu:fb93f08 antibody, zgc:77284 antibody, Spred-2 antibody, C79158 antibody, sprouty related EVH1 domain containing 2 antibody, sprouty related, EVH1 domain containing 2 antibody, sprouty-related, EVH1 domain containing 2b antibody, sprouty-related, EVH1 domain containing 2 antibody, SPRED2 antibody, spred2 antibody, spred2b antibody, Spred2 antibody
Background
Spred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. At least two isoforms of Spred2 are known to exist.Synonyms: MGC163164, Spred-2, Sprouty-related EVH1 domain containing 2
Gene ID
200734
NCBI Accession
NP_861449
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