Synaptogyrin 1 antibody (Center)

Catalog No. ABIN500843

Product Details anti-Synaptogyrin 1 Antibody

Target: Synaptogyrin 1 (SYNGR1)

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptogyrin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Synaptogyrin-1 / SYNGR1.

Purification: Peptide affinity chromatography

Immunogen: SYNGR1 antibody was raised against a 16 amino acid peptide from near the center of human SYNGR1.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Synaptogyrin 1

Target: Synaptogyrin 1 (SYNGR1)

Alternative Name: Synaptogyrin-1 / SYNGR1 (SYNGR1 Products)

Background: Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia, however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.

Gene ID: 9145

Pathways: Regulation of long-term Neuronal Synaptic Plasticity