TLR9 antibody (Center)
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- Target See all TLR9 Antibodies
- TLR9 (Toll-Like Receptor 9 (TLR9))
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Binding Specificity
- Center
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TLR9 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects CD289 / TLR9 at center.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Peptide affinity chromatography
- Immunogen
- TLR9 antibody was raised against a peptide corresponding to 15 amino acids near the center of human TLR9.
- Isotype
- IgG
- Top Product
- Discover our top product TLR9 Primary Antibody
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- Application Notes
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ELISA. Western blot: 0.5 to 1 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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Repetitive extragenic palindromic DNA sequences from Brucella melitensis stimulate Toll-like receptor 9 signaling in macrophages." in: Molecular medicine reports, Vol. 15, Issue 1, pp. 271-276, (2017) (PubMed).
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Repetitive extragenic palindromic DNA sequences from Brucella melitensis stimulate Toll-like receptor 9 signaling in macrophages." in: Molecular medicine reports, Vol. 15, Issue 1, pp. 271-276, (2017) (PubMed).
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- Target
- TLR9 (Toll-Like Receptor 9 (TLR9))
- Alternative Name
- CD289 / TLR9 (TLR9 Products)
- Synonyms
- CD289 antibody, toll like receptor 9 antibody, toll-like receptor 9 antibody, TLR9 antibody, Tlr9 antibody
- Background
- Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). TLR9 forms a subfamily along with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences (3) and are localized in intracellular acidic compartments such as the phagolysosome (4). Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection (5), TLR9 is strictly dependent on MyD88 (3).Synonyms: Toll-like receptor 9, UNQ5798/PRO19605
- Gene ID
- 54106
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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