SF3A2 antibody (AA 65-160) (AbBy Fluor® 680)

Catalog No. ABIN5010220

The Rabbit Polyclonal anti-SF3A2 antibody is suitable to detect SF3A2 in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for SF3A2 antibody (AA 65-160) (AbBy Fluor® 680) (ABIN5010220)

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A2 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SF3A2 Antibody (AbBy Fluor® 680)

Binding Specificity: AA 65-160

Purpose: SAP62 Polyclonal Antibody, AbBy Fluor-680 Conjugated

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAP62

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SF3A2

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Alternative Name: SAP62

Background:

Synonyms: PRP11, SAP62, PRPF11, SF3a66, Splicing factor 3A subunit 2, Spliceosome-associated protein 62, SAP 62, SF3A2

Background: Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.

Gene ID: 8175

UniProt: Q15428

Pathways: Ribonucleoprotein Complex Subunit Organization