SF3A2 antibody (AA 65-160) (AbBy Fluor® 680)

Catalog No. ABIN5010220

The Rabbit Polyclonal anti-SF3A2 antibody is suitable to detect SF3A2 in samples from Mouse and Rat. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for SF3A2 antibody (AA 65-160) (AbBy Fluor® 680) (ABIN5010220)

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A2 antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SF3A2 Antibody (AbBy Fluor® 680)

Binding Specificity: AA 65-160

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAP62

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SF3A2

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Alternative Name: SAP62

Background:

Synonyms: PRP11, SAP62, PRPF11, SF3a66, Splicing factor 3A subunit 2, Spliceosome-associated protein 62, SAP 62, SF3A2

Background: Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.

Gene ID: 8175

UniProt: Q15428

Pathways: Ribonucleoprotein Complex Subunit Organization