SF3A2 antibody (AA 166-194)

Catalog No. ABIN1881795

Product Details anti-SF3A2 Antibody

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Binding Specificity: AA 166-194

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SF3A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human SF3A2.

Clone: RB42212

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-SF3A2 antibody (ABIN1881795)

Tanackovic, Krämer: "Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo." in: Molecular biology of the cell, Vol. 16, Issue 3, pp. 1366-77, (2005) (PubMed).

Takenaka, Nakagawa, Miyamoto, Miki: "The pre-mRNA-splicing factor SF3a66 functions as a microtubule-binding and -bundling protein." in: The Biochemical journal, Vol. 382, Issue Pt 1, pp. 223-30, (2004) (PubMed).

Target Details for SF3A2

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Alternative Name: SF3A2 (SF3A2 Products)

Synonyms: SAP62 antibody, SF3a66 antibody, sf3a2 antibody, MGC52805 antibody, prp11 antibody, prpf11 antibody, sap62 antibody, sf3a66 antibody, SF3A2 antibody, 66kDa antibody, AW047242 antibody, PRP11 antibody, SFA66 antibody, Sap62 antibody, PRPF11 antibody, splicing factor 3a subunit 2 antibody, splicing factor 3a subunit 2 S homeolog antibody, splicing factor 3a, subunit 2 antibody, SF3A2 antibody, sf3a2.S antibody, sf3a2 antibody, Sf3a2 antibody

Background: This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.

Molecular Weight: 49256

NCBI Accession: NP_009096

UniProt: Q15428

Pathways: Ribonucleoprotein Complex Subunit Organization