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KCNK18 antibody (Potassium Channel Subfamily K Member 18) (Center) Primary Antibody

KCNK18 Reactivity: Human, Mouse, Rat EIA, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN501034
$511.50
Plus shipping costs $45.00
0.1 mg
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  • Target
    KCNK18
    Binding Specificity
    Center
    • 9
    • 9
    • 9
    • 7
    • 1
    • 1
    • 1
    Reactivity
    Human, Mouse, Rat
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This KCNK18 antibody is un-conjugated
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    • 28
    • 23
    • 22
    • 5
    • 1
    • 1
    • 1
    • 1
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    TRESK antibody was raised against a 17 amino acid peptide from near the center of human TRESK.
    Isotype
    IgG
  • Application Notes
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    KCNK18
    Alternative Name
    KCNK18 (KCNK18 Antibody Abstract)
    Synonyms
    K2p18.1, MGR13, TRESK, TRESK-2, TRESK2, TRIK, Gm781, Tresk, Tresk-2, Trik, potassium two pore domain channel subfamily K member 18, potassium channel, subfamily K, member 18, KCNK18, Kcnk18
    Background
    TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.Synonyms: KCNK18, Potassium channel subfamily K member 18, TRESK, TRIK, TWIK-related individual potassium channel, TWIK-related spinal cord potassium channel
    Gene ID
    338567
    NCBI Accession
    NP_862823
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