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KCNK18 antibody (AA 210-260)

KCNK18 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991251
  • Target See all KCNK18 Antibodies
    KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    AA 210-260
    Reactivity
    Human, Mouse, Rat
    Host
    • 22
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNK18 antibody is un-conjugated
    Application
    • 15
    • 13
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    TRESK Antibody is affinity chromatography purified via peptide column.
    Immunogen
    TRESK antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRESK. The immunogen is located within amino acids 210 - 260 of TRESK.
    Isotype
    IgG
    Top Product
    Discover our top product KCNK18 Primary Antibody
  • Application Notes
    TRESK antibody can be used for detection of TRESK by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    TRESK Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    TRESK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))
    Alternative Name
    TRESK (KCNK18 Products)
    Synonyms
    K2p18.1 antibody, MGR13 antibody, TRESK antibody, TRESK-2 antibody, TRESK2 antibody, TRIK antibody, Gm781 antibody, Tresk antibody, Tresk-2 antibody, Trik antibody, potassium two pore domain channel subfamily K member 18 antibody, potassium channel, subfamily K, member 18 antibody, KCNK18 antibody, Kcnk18 antibody
    Background
    TRESK Antibody: TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
    Gene ID
    338567
    NCBI Accession
    NP_862823
    UniProt
    Q7Z418
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