TTC5 antibody (C-Term)

Catalog No. ABIN501091

This Rabbit Polyclonal antibody specifically detects TTC5 in WB, IHC (p) and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for TTC5 antibody (C-Term) (ABIN501091)

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-TTC5 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects TTC5

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography

Immunogen: TTC5 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human TTC5.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for TTC5

Target: TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))

Alternative Name: TTC5

Background: Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats (1). Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 (2) and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5 (3), suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.Synonyms: TPR repeat protein 5, Tetratricopeptide repeat protein 5

Gene ID: 91875

UniProt: Q8N0Z6

Pathways: Chromatin Binding