Calretinin antibody (AA 4-238)

Catalog No. ABIN5027071

The Rabbit Polyclonal anti-Calretinin antibody is suitable to detect Calretinin in samples from Human. It has been validated for WB.

Quick Overview for Calretinin antibody (AA 4-238) (ABIN5027071)

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calretinin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Calretinin Antibody

Binding Specificity: AA 4-238

Purification: Protein A Chromatography

Immunogen: A partial length recombinant Calretinin protein (amino acids 4-238) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for Calretinin

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Alternative Name: Calretinin

Background: Calretinin is a 29-kD intracellular, vitamin D-dependent calcium binding protein that likely has multiple functional roles including intracellular calcium buffering and message targeting. This protein is a member of the EF-hand family of calcium-binding proteins and first identified in the central nervous system. It has also been identified in a wide variety of non-neural cells, both neoplastic and non-neoplastic. In the oncologic arena calretinin is most commonly used as part of a panel in the separation of pleural mesothelioma from poorly differentiated pulmonary adenocarcinomas. While in most cases highly sensitive and specific for mesothelial origin, calretinin positivity has been reported in carcinomas arising in a myriad of other tissues including ovary, testis, adrenal cortex, colon, breast, sinonasal tract, thymus, skin and even soft tissue.

Molecular Weight: 31 kDa

Gene ID: 794

UniProt: P22676