DPPA4 antibody (AA 1-206)
Quick Overview for DPPA4 antibody (AA 1-206) (ABIN5027166)
Target
See all DPPA4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-206
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Purification
- Protein A Chromatography
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Immunogen
- A partial length recombinant DPPA4 protein (amino acids 1-206) was used as the immunogen for this antibody.
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Isotype
- IgG
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Application Notes
- WB: 1-2 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))
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Alternative Name
- DPPA4
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Background
- DPPA4 (Developmental pluripotency-associated 4) is a DNA binding SAP domain-containing protein. It is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers. It is also mutated in some cancers. DPPA4 overexpression induces cell proliferation through genes related to regulation of G1/S transition. DPPA4 contains a functional HMG/POU cassette and behaves as a Sox2:Oct-3/4 target gene. Sox2 and Oct-3/4 function as master regulators during mammalian embryogenesis.
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Molecular Weight
- 42 kDa
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Gene ID
- 55211
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UniProt
- Q7L190
Target
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